Tired Eyes, Modern Solutions
Dark circles, puffiness, and hollow under-eyes can make even the most rested face look tired.
Traditionally, Tear Trough Filler has been the go-to option, adding instant volume with hyaluronic acid. But as the aesthetics industry evolves, many patients now seek a more natural, regenerative approach.
Enter Polynucleotides under eyes treatment! A new kind of injectable treatment helps improve your skin. It uses science to rebuild collagen, elastin, and hydration from within.
At Skinfinity Leeds, we offer both treatments help you choose the safest and most effective route for your unique skin.
Book your under eye consultation here!
What Are Polynucleotides (Plinest® by Mastelli)?
Polynucleotides are naturally derived DNA fragments (from fish) that stimulate your skin’s own collagen and elastin production.
Unlike filler, they don’t add volume they improve the skin itself, by boosting collagen production.
When injected into the delicate eye area, Plinest Polynucleotides encourage cell regeneration, deep hydration, and improved skin texture.
They’re particularly effective for:
- Fine lines and crepey under-eye skin
- Mild puffiness and dark circles
- Dullness and dehydration
- Post-filler correction or prevention of overfilling
How it works: Polynucleotides work as biostimulators, prompting fibroblasts to produce new collagen and elastin. Over time, the skin becomes firmer, brighter, and smoother with zero added volume.
Read about polynucleotides here.
What Is Tear Trough Filler?
Tear Trough Filler is a dermal filler made from hyaluronic acid. It is placed under the eyes to reduce hollowness and shadows.
It’s ideal for people who have true volume loss in the under-eye area and good skin elasticity.
How it works: The filler restores lost structure by gently filling depressions beneath the eye, reflecting light better and reducing dark circles.
While it delivers instant gratification, fillers don’t improve the skin’s quality they simply replace lost volume. For patients with thinner or crepey skin, this can sometimes lead to lumpiness or prolonged puffiness. Tear trough fillers have a high complication rate - usually do to poor patient selection.
Learn more about dermal fillers here.
Comparison: Polynucleotides Injections vs Tear Trough Filler
Book your under eye treatment today!
Polynucleotides (Plinest)
- Before: Skin appears thin, tired, or finely lined under the eyes.
- After 1 session (2–3 weeks): Subtle hydration boost; mild smoothing.
- After 2–3 sessions (6–8 weeks): Noticeably firmer, brighter, more even skin tone.
- At 3 months: Full collagen stimulation visible — reduced crepiness and fine lines.
- Maintenance: 1 top-up every 6–12 months for long-term improvement.
Tear Trough Filler
- Before: Visible hollows or shadows beneath the eye.
- Immediately after treatment: Instant volume restoration and brighter under-eye area.
- At 2 weeks: Filler has integrated into tissue; natural, refreshed appearance.
Maintenance: Every 9–12 months depending on product and metabolism.
Which Is Right for You Polynucleotides or Tear Trough Filler?
At Skinfinity Leeds, every under-eye treatment begins with a personalised treatment plan.
Your doctor will assess:
- Skin texture and elasticity
- Volume loss vs skin laxity
- Medical history and treatment goals
If your main issue is crepey skin or early ageing, Polynucleotide treatment may be best.
If you have deep hollows or shadowing, Tear Trough Filler may deliver faster results.
Many patients benefit from a combination approach, using both treatments strategically to balance structure and skin quality.
Safety, Side Effects & Recovery
Both treatments are minimally invasive and doctor-delivered at Skinfinity.
You may experience:
- Mild redness or swelling in the treated area
- Temporary bruising or tenderness
These effects typically resolve within 24–48 hours.
Because Plinest stimulates natural healing, results continue to develop even after recovery.
Long-Term Results & Maintenance
Both treatments are non-surgical and fit easily around busy lifestyles.
- Polynucleotides offer progressive, long-term regeneration.
- Filler gives immediate structure and lift.
Many patients switch from fillers to Polynucleotides for their maintenance treatment over time. They focus on skin quality instead of instant volume.
Your Consultation at Skinfinity Leeds
Doctor-led aesthetic care means every treatment plan is tailored to your anatomy and long-term skin health.
At Skinfinity Thorpe Approach Leeds, we use Plinest Polynucleotides. These have been tested by Mastelli and are trusted in Europe for safe, natural rejuvenation.
Book your consultation and discover if Polynucleotides or Tear Trough Filler is right for you.
Learn more about:
Polynucleotides Salmon Sperm Facial Treatment - Read the full blog here.
How Sunekos skin booster can improve under eye dark circles here.
View our full treatments and prices here.
FAQs
How long do Polynucleotides take to work under eyes?
You’ll usually start to see visible improvements within 2–4 weeks after your first session as collagen production increases. The skin continues to improve gradually with each treatment.
How long do Polynucleotides last under eyes?
Results typically last 9–12 months, depending on age, skin condition, and lifestyle. Maintenance sessions every 6–12 months help sustain brightness and elasticity.
How many sessions of Polynucleotides do you need for under eyes?
Most patients need 2–3 sessions, spaced about 3–4 weeks apart, to achieve optimal results. Your practitioner will tailor your treatment plan based on skin quality and concerns.
What do Polynucleotides do under eyes?
They improve skin texture, firmness, and hydration while reducing the appearance of fine lines and dullness. Think of them as a “skin reset” — helping the tissue repair itself for naturally smoother, tighter skin.
Are Polynucleotides better than Tear Trough Filler?
It depends on your concern. Polynucleotides treat skin quality, while fillers treat volume loss. If your under eyes are hollow or deeply shadowed, filler may be best. If your skin looks thin, crepey, or tired, Polynucleotides are the better choice — and the two can often be combined for a balanced, natural result.
Why do my eyes look worse after Polynucleotides?
It’s common for the area to appear slightly puffy or uneven for a few days after treatment — this is normal and temporary. Swelling settles as the product integrates and begins repairing the skin. Always ensure your treatment is performed by a medical professional experienced in this delicate area.
How much are Polynucleotides under eyes?
Prices vary depending on the clinic and product used (e.g. Plinest®, Plinest Eye®). Expect to pay around £250–£350 per session in most medical aesthetics clinics.
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